Currently, this is the central focus of most of the work in the laboratory.
Structural Basis for Prolactin and Growth Hormone Receptor Activation
Two human protein hormone/cytokines, prolactin and growth hormone, have served as our central model for investigating the structural and thermodynamic/kinetic basis of protein function.
Ca2+-binding/sensing Domains in the Polycystin-1/2 'TRP' Channel Family
Polymorphic drug-metabolizing enzymes.
TUG
Ataxin-3
Phosphoinositide metabolism